Dear Dr. Simon, I'm sorry to give you messed up numbers of OLIKARD's dosage. 3 tab (40 mg) a day now is the co…

Question

Dear Dr. Simon, I'm sorry to give you messed up numbers of OLIKARD's dosage. 3 tab (40 mg) a day now is the correct figure. Don't you think I am already a good case to investigate the connection between cardiac disorder and CML. I appreciate you're working on this problem. The cardiologysts I've contacted know little of this problem and are not prepared to take the risk. What about Monopril or am I confusing something? Regards and thanks Eugene- the- grambler

Мацкеплишвили С.Т. · Answer

Dear Eugene- the- grambler! Generally it is not advised to take mononitrates (Olicard, Monocinque etc. ) three or more times a day. Due to the specific pharmacokinetics and liver elimination profiles, frequent administration produces rapid nitrate tolerance with limited action. Thus, the interval before doses should be 8 hours or more for the sustained antianginal effect. As for the cardiac disease and CML – many things depend on the immunosuppressive treatment (in any) for the latter and there is no risk for coronary angiography. Why don’ t you visit us for an hour or two to make things clear. Sincerely, S. M. PS. Monopril is an ACE inhibitor just like Prestarium or Tritace with no apparent advantages.

Grumbler · Answer

Dear Dr. Simon, Thanks for your patience and detailed guidance. What am I supposed to do to 'switch' to your Center. As a matter of fact you're totally unreachable on the office phone, Sir, with due respect. .. . As to Mononitrates I'm following the orders of other professionals. I'M READY TO MEET YOU. regards Euge- the- Grumbler

Область поиска

Ответы

Ответить